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Polynucleotide Ligases

More information in Books or onNLM PubMed
Definition: Catalyze the joining of preformed ribonucleotides or deoxyribonucleotides in phosphodiester linkage during genetic processes. EC 6.5.1.  do not confuse X ref POLYNUCLEOTIDE SYNTHETASES with X refs POLYRIBONUCLEOTIDE SYNTHETASE or POLYDEOXYRIBONUCLEOTIDE SYNTHETASES   
Examples DNA Ligases; RNA Ligase (ATP)
Other names Polynucleotide Synthetases; Synthetases, Polynucleotide; Ligases, Polynucleotide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
R3C ligase  EC 6.5.1.-   *Polynucleotide Ligases *RNA, Catalytic. Proc Natl Acad Sci U S A 2002 Oct 1;99(20):12733-40
band V ligase  EC 6.5.1.-   *Polynucleotide Ligases. EMBO J 2001 Sep 3;20(17):4694-703
band IV ligase  EC 6.5.1.-   *Polynucleotide Ligases. EMBO J 2001 Sep 3;20(17):4694-703
tRNA ligase, yeast  0   *Phosphoric Diester Hydrolases *Polynucleotide 5'-Hydroxyl-Kinase *Polynucleotide Ligases. Biochemistry 1988;27(24):8852
poly C synthetase  EC 6.5.-   *Polynucleotide Ligases. Biochem Pharmacol 23(2):369;1974
oligoisoadenylate synthetase E  EC 6.5.1.-   *Polynucleotide Ligases. Proc Natl Acad Sci USA 76(7):3208
(2'-5')oligo-isoadenylate synthetase  EC 6.5.1.-   *Polynucleotide Ligases. FEBS Lett 95(2):257;1978; Proc Natl Acad Sci USA 75(10):4734;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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