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Platelet Factor 4

More information in Books or onNLM PubMed
Definition: A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.     
Pharmacological Action Coagulants 		Other names Chemokine CXCL4; CXCL4 Chemokine; Antiheparin Factor; gamma Thromboglobulin; Chemokine, CXCL4; CXCL4, Chemokine; gamma-Thromboglobulin; PF4 (Platelet Factor 4); Heparin Neutralizing Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
platelet factor 4 (47-70)  0   *Peptide Fragments *Platelet Factor 4. FASEB J 2001 Mar;15(3):550-2
C18G peptide  0   *Peptides Platelet Factor 4. Cancer Chemother Pharmacol 1993;32(2):109-15
recombinant PF4-241  136512-13-5   *Platelet Factor 4 Recombinant Proteins. Cancer Res 1991;51(8):2077
PF4V1 protein, human  0   *Platelet Factor 4. Blood 1990;76(2):336
platelet factor 4 (59-70)  88145-47-5 L-Serine, N-(N-(N-(N-(N2-(N2-(N-(N-(N2-(N2-(N-L-leucyl-L-tyrosyl)-L-lysyl)-L-lysyl)-L-isoleucyl)-L-isoleucyl)-L-lysyl)-L-lysyl)-L-leucyl)-L-leucyl)-L-alpha-glutamyl)-, (6R-(6alpha,7beta(Z)))  *Peptide Fragments *Platelet Factor 4. Immunology 1985;54(1):163

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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