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Phenylalanine Hydroxylase

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Definition: An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.  /defic: consider also PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL   
See Also Phenylketonuria, Maternal; Phenylketonurias 		Other names Phenylalanine 4 Monooxygenase; Phenylalanine 4 Hydroxylase; Hydroxylase, Phenylalanine; 4-Monooxygenase, Phenylalanine; 4-Hydroxylase, Phenylalanine; Phenylalanine 4-Monooxygenase; Phenylalanine 4-Hydroxylase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3,4-dihydroxystyrene  6053-02-7   *Styrenes Phenylalanine Hydroxylase/antagonists & inhibitors Tryptophan Hydroxylase/antagonists & inhibitors Tyrosine 3-Monooxygenase/antagonists & inhibitors. Biochim Biophys Acta 1984;789(2):111

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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