Peptide Elongation Factor Tu (definition)

encyclopedia of medical concepts

ψ
ψ
ψ

Peptide Elongation Factor Tu

More information in Books or on

Definition: A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.

coordinate with MITOCHONDRIAL PROTEINS or BACTERIAL PROTEINS if pertinent

Other names Elongation Factor Tu; eEF Tu; Factor Tu, Elongation; EF Tu; eEF-Tu; Protein Synthesis Elongation Factor Tu; Eucaryotic Elongation Factor Tu; EF-Tu

Substance	CAS Registry & name	Categories	Source
tufB protein, E coli	EC 3.6.1.-	Peptide Elongation Factor Tu Escherichia coli Proteins.
Tufm protein, mouse	EC 3.6.1.-	Peptide Elongation Factor Tu Mitochondrial Proteins.
TUF1 protein, S cerevisiae	EC 3.6.1.-	Peptide Elongation Factor Tu Mitochondrial Proteins *Saccharomyces cerevisiae Proteins.
Tufm protein, rat	EC 3.6.1.-	Peptide Elongation Factor Tu Mitochondrial Proteins.
tuf1 protein, S pombe	EC 3.6.1.-	Peptide Elongation Factor Tu Mitochondrial Proteins *Schizosaccharomyces pombe Proteins.
ef1a-a protein, S pombe	EC 3.6.1.-	Peptide Elongation Factor Tu Schizosaccharomyces pombe Proteins.
TUFA protein, Arabidopsis	EC 3.6.1.-	Peptide Elongation Factor Tu Mitochondrial Proteins *Arabidopsis Proteins.
tuf3 protein, Streptomyces coelicolor	0	Bacterial Proteins Peptide Elongation Factor Tu.	Microbiology 1995 Oct;141(Pt 10):2519-28
TUFM protein, human	0	Peptide Elongation Factor Tu Mitochondrial Proteins.	FEBS Lett 1995 Jan 23;358(2):119-25
mocimycin	50935-71-2	Pyridones Peptide Elongation Factor Tu. Pharma Action Anti-Bacterial Agents	Biochemistry 1980;19(5):865; Eur J Biochem 89(2):557;1978; Europ J Biochem 75:55;1977; Europ J Biochem 75:67;1977; Europ J Biochem 86:153;1978; FEBS Lett 81(2):303;1977; FEBS Lett 98(1):111;1979; Helv Chim Acta 57(1):212;1974; J Am Chem Soc 95(25):8449;1973; J Bacteriol 135(3):1107;1978; Proc Nat Acad Sci USA 71(12):4910;1974; Proc Nat Acad Sci USA 74(10):4341;1977; Proc Nat Acad Sci USA 74(8):3264;1977; Proc Nat Acad Sci USA 75(9):4470;1978

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link

Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy