encyclopedia of medical concepts
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Paraplegia

More information in Books or onNLM PubMed
Definition: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.  also available is QUADRIPLEGIA; note X ref spastic paraplegia: SPASTIC PARAPLEGIA, HEREDITARY is also available   
Examples Brown-Sequard Syndrome
Other names Spastic Paraplegia; Paraplegia, Spastic; Paralysis, Lower Extremities; Spinal Paraplegias; Spinal Paraplegia; Spastic Paraplegias; Paraplegias, Spinal; Paraplegias, Spastic; Paraplegias, Flaccid; Paraplegias, Cerebral; Paraplegias, Ataxic; Paraplegias; Flaccid Paraplegias; Flaccid Paraplegia; Cerebral Paraplegias; Cerebral Paraplegia; Ataxic Paraplegias; Ataxic Paraplegia; Paraplegia, Spinal; Paraplegia, Flaccid
 
SubstanceCAS Registry & nameCategoriesSource
KIAA0196 protein, human  0   *Proteins Paraplegia. Am J Hum Genet 2007 Jan;80(1):152-61
ZFYVE27 protein, human  0   *Vesicular Transport Proteins Paraplegia. Am J Hum Genet 2006 Aug;79(2):351-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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