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Osteoarthropathy, Primary Hypertrophic

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Definition: A conditioned chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, seborrhea, hyperhidrosis, periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. It is believed to be inherited as an autosomal dominant trait. (From Dorland, 27th ed)  OSTEOARTHROPATHY, SECONDARY HYPERTROPHIC is also available    Other names Pachydermoperiostosis; Primary Hypertrophic Osteoarthropathy; Primary Hypertrophic Osteoarthropathies; Pachydermoperiostoses; Osteoarthropathy, Idiopathic Hypertrophic; Osteoarthropathies, Primary Hypertrophic; Osteoarthropathies, Idiopathic Hypertrophic; Idiopathic Hypertrophic Osteoarthropathies; Hypertrophic Osteoarthropathy, Primary; Hypertrophic Osteoarthropathy, Idiopathic; Hypertrophic Osteoarthropathies, Primary; Hypertrophic Osteoarthropathies, Idiopathic; Idiopathic Hypertrophic Osteoarthropathy
 
SubstanceCAS Registry & nameCategoriesSource
Reginato Schiapachasse syndrome  0   *Osteoarthropathy, Primary Hypertrophic Cranial Sutures/abnormalities.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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