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Nucleoside-Phosphate Kinase

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Definition: An enzyme that catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside monophosphate, e.g., UMP, to form ADP and UDP. Many nucleoside monophosphates can act as acceptor while many ribo- and deoxyribonucleoside triphosphates can act as donor. EC 2.7.4.4.      Other names Nucleoside Phosphate Kinase; Monophosphate Kinases, Nucleoside; Kinases, Nucleoside Monophosphate; Kinase, Nucleoside-Phosphate; Nucleoside Monophosphate Kinases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Dpt1 protein, Arabidopsis  EC 2.7.4.-   *Nucleoside-Phosphate Kinase *Arabidopsis Proteins. Plant Mol Biol 2009 Mar;69(5):517-28
cytidylate kinase 2, human  EC 2.7.4.14   *Nucleoside-Phosphate Kinase. J Biol Chem 2008 Jan 18;283(3):1563-71
MPP5 protein, human  EC 2.7.4.8   *Membrane Proteins *Nucleoside-Phosphate Kinase. J Biol Chem 2005 Apr 8;280(14):13584-92
Mpp5 protein, mouse  EC 2.7.4.8   *Membrane Proteins *Nucleoside-Phosphate Kinase. J Comp Neurol 2005 Jan 3;481(1):31-41
MAGI protein, Drosophila  EC 2.7.4.8   *Nucleoside-Phosphate Kinase *Drosophila Proteins. Gene Expr Patterns 2002 Dec;2(3-4):289-96
MPP4 protein, human  EC 2.7.4.8   *Eye Proteins *Membrane Proteins *Nucleoside-Phosphate Kinase. Genomics 2001 Jun 15;74(3):377-84
hydroxymethyldeoxyuridinemonophosphate kinase  EC 2.7.4.-   *Nucleoside-Phosphate Kinase. J Virol 1980;34(2):347
uridine monophosphate kinase  EC 2.7.4.-   *Nucleoside-Phosphate Kinase. Acta Med Okayama 30(4):221;1976; Am J Human Genet 26(5):627;1974; Ann Hum Biol 6(3):241;1979; Ann Hum Genet 43(2):121;1979; Biochim Biophys Acta 302(1):38;1973; Cancer Res 37:1593;1977; Cytogenet Cell Genet 14(3-6):329;1975; Cytogenet Cell Genet 15(3):146;1975; J Bacteriol 137(3):1073;1979; Radiobiologiia 16(3):323;1976
nucleoside triphosphate-adenylate kinase  EC 2.7.4.10   *Nucleoside-Phosphate Kinase. Eur J Biochem 93(2):257;1979; Eur J Biochem 93(2):263;1979
5-hydroxymethyldeoxycytidylate kinase  EC 2.7.4.-   *Nucleoside-Phosphate Kinase.
dTMP kinase  EC 2.7.4.9   *Nucleoside-Phosphate Kinase. Biochem Biophys Res Commun 1979;91(3):1196; Biochemistry 12(14):2612;1973; Biochimie 58(9):1135;1976; Cancer Res 1980;40(4):1235; Cancer Res 36(1):37;1974; Cancer Res 37:1593;1977; Chem Biol Interact 25(2-3):355;1979; Enzyme 24(1):54;1979; J Biochem (Tokyo) 1979;86(3):657; J Biochem (Tokyo) 252(16):5686;1977; J Biol Chem 251(21):6555;1976; J Biol Chem 253(5):1325;2978; J Virol 30(3):942;1979; Somatic Cell Genet 4(2):169;1978
cytidylate kinase  EC 2.7.4.14   *Nucleoside-Phosphate Kinase. Anal Biochem 60(2):645;1974; Biochim Biophys Acta 429(1):182;1976; Cancer Res 37:1593;1977; Cancer Res 38:579;1978; Methods Enzymol 51:321;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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