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Myeloproliferative Disorders

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Definition: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.  myelo- here   
See Also Leukemia
Examples Anemia, Myelophthisic; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Neutrophilic, Chronic; Leukemoid Reaction; Polycythemia Vera; Primary Myelofibrosis; Thrombocytosis
Other names Myeloproliferative Disorder; Disorders, Myeloproliferative; Disorder, Myeloproliferative

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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