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Methimazole

More information in Books or onNLM PubMed
Definition: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.     
Pharmacological Action Antithyroid Agents 		Other names Thiamazole; Methymazol; Hexal, Thiamazol; Henning, Thiamazol; 1 Methyl 2 mercaptoimidazole; Tirodril; Tiamazol; Thyrozol; Thimazol; Thiamazol Hexal; Thiamazol Henning; Temmler Brand of Methimazole; Tapazole; Sanofi Synthelabo Brand of Methimazole; Philopharm Brand of Methimazole; Strumazol; Nourypharma Brand of Methimazole; Metizol; Metisol; MethylmercaptoimidazoleDrugs* : TAPAZOLE; METHIMAZOLE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
phenyl methimazole  0   *Thiones Methimazole/*analogs & derivatives. J Immunol 2004 Aug 1;173(3):2041-9
1-methyl-3-propylimidazole-2-thione  135011-47-1   Methimazole/*analogs & derivatives. Fundam Appl Toxicol 1995 Sep;27(2):185-94
2-mercapto-1-methyl-5-methylmercaptoimidazole  0   Methimazole/*analogs & derivatives. Xenobiotica 1984;13(11):661

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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