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Mannosidases

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Definition: Glycoside hydrolases that catalyze the hydrolysis of alpha or beta linked MANNOSE.  ALPHA-MANNOSIDASE and BETA-MANNOSIDASE are also available; /defic: consider also MANNOSIDASE DEFICIENCY DISEASES   
Examples alpha-Mannosidase; beta-Mannosidase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Mnl2 protein, S cerevisiae  EC 3.2.1.-   *Mannosidases *Saccharomyces cerevisiae Proteins. Biochem Biophys Res Commun. 2011 Oct 28;414(3):528-32.
ERManI protein, human  EC 3.2.1.-   *Mannosidases. Carbohydr Res. 2006 Sep 25;341(13):2233-45.
endomannosidase, rat  EC 3.2.1.-   *Mannosidases *Membrane Proteins. Cell Mol Life Sci 2008 May;65(10):1609-19
endoplasmic reticulum alpha-mannosidase I, human  EC 3.2.1.114   *Mannosidases. J Org Chem. 2005 Nov 25;70(24):9892-904
MAN2C1 protein, human  EC 3.2.1.24   *Mannosidases. Mol Vis 2006;12:499-505
alpha-1-2-endomannosidase, rat  EC 3.2.1.-   *Mannosidases *Membrane Proteins. Glycobiology 2005 Jun;15(6):615-24
alpha-1-2-endomannosidase, human  EC 3.2.1.-   *Mannosidases *Membrane Proteins. Glycobiology 2005 Jun;15(6):615-24
Man2a2 protein, mouse  EC 3.2.1.114   *Mannosidases.
DCW1 protein, S cerevisiae  EC 3.2.1.101   *Mannosidases *Membrane Glycoproteins *Saccharomyces cerevisiae Proteins. Mol Microbiol 2002 Nov;46(4):1011-22
MAN2A2 protein, human  EC 3.2.1.114   *Mannosidases. Science 2002 Jan 4;295(5552):124-7
MNL1 protein, S cerevisiae  EC 3.2.1.-   *Mannosidases *Saccharomyces cerevisiae Proteins. EMBO Rep 2001 May;2(5):423-30
aminocyclitol alpha-mannosidase  EC 3.2.1.-   *Mannosidases. Bioorg Med Chem Lett 2000 May 15;10(10):1047-50
5-amino-4-O-methyl-1,2,3,4-cyclopentanetetrol  0   *Cyclopentanes Mannosidases/antagonists & inhibitors. Bioorg Med Chem Lett 2000 May 15;10(10):1047-50
beta-1,4-mannosidase  EC 3.2.1.-   *Mannosidases. Anal Biochem 2000 Jul 1;282(2):165-72
6-methoxycarbonyl-4-pivaloyloxy-2-(pivaloyloxymethyl)bicyclo(3.1.0)hex-2-ene-1-carboxylic acid  0   *Carboxylic Acids *Cyclopropanes Mannosidases/antagonists & inhibitors. Acta Crystallogr C 2000 Mar;56 ( Pt 3):358-9
endo-beta-mannosidase  EC 3.2.1.-   *Mannosidases. J Biochem (Tokyo) 1999 Feb;125(2):363-7
1-deoxy-3-O-(5-thioglucopyranosyl)mannojirimycin  0   *Glucosides 1-Deoxynojirimycin/*analogs & derivatives Mannosidases/antagonists & inhibitors. Bioorg Med Chem Lett 1998 May 19;8(10):1215-20
1-deoxy-3-S-(1-thioglucopyranosyl)mannojirimycin  0   *Glucosides 1-Deoxynojirimycin/*analogs & derivatives Mannosidases/antagonists & inhibitors. Bioorg Med Chem Lett 1998 May 19;8(10):1215-20
mannan endo-1,4-beta-mannosidase, Bacillus circulans  EC 3.2.1.78   *Bacterial Proteins *Mannosidases. Biosci Biotechnol Biochem 1998 Mar;62(3):514-20
galactomannanase  EC 3.2.1.-   *Mannosidases. Biochem Soc Trans 1997 Aug;25(3):378S
alpha(1-6)mannosidase  EC 3.2.1.-   *Mannosidases. J Biol Chem 1992 May 15;267(14):9706-12
aryl-alpha-mannosidase  EC 3.2.1.-   *Mannosidases. Glycobiology 1990 Sep;1(1):71-82
rhamnanase  EC 3.2.1.-   *Mannosidases. J Bacteriol 1992 Apr;174(7):2407-11
alpha1-2,alpha1-3,alpha1-6-mannosidase  EC 3.2.1.-   *Mannosidases. Eur J Biochem 1991;197(1):229
glycoprotein endo-alpha-1,3-mannosidase  EC 3.2.1.130   *Mannosidases. Arch Biochem Biophys 1990;277(1):114
mannostatin B  102822-66-2 1,2,3-Cyclopentanetriol, 4-amino-5-(methylsulfinyl)  *Cyclopentanes Mannosidases/antagonists & inhibitors. J Antibiot (Tokyo) 1989;42(6):883
mannostatin A  102822-56-0 1,2,3-Cyclopentanetriol, 4-amino-5-(methylthio)  *Cyclopentanes Mannosidases/antagonists & inhibitors. J Antibiot (Tokyo) 1989;42(6):883
endo-alpha-D-mannosidase  EC 3.2.1.-   *Mannosidases. J Biol Chem 1987;262(8):3775
mannan 1,2-(1,3)-alpha mannosidase  EC 3.2.1.77   *Mannosidases. Mikrobiologiia 1986;55(1):81
1,4-dideoxy-1,4-iminomannitol  95189-02-9   Mannitol/*analogs & derivatives Imino Furanoses Mannosidases/antagonists & inhibitors. Arch Biochem Biophys 1985;243(1):35
mannosyl-oligosaccharide 1,2-alpha-mannosidase  EC 3.2.1.113   *Mannosidases. Eur J Biochem 1985;150(1):41
endo-1,4-beta-D-mannanase  EC 3.2.1.78   *Mannosidases. Biochem J 1984;219(3):857
mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase  EC 3.2.1.114   *Mannosidases. Gene 1995 Mar 10;154(2):183-6; Proc Natl Acad Sci U S A 1983;80(14):4364
exo-1,4-beta-mannanase  EC 3.2.1.-   *Mannosidases. J Biochem 1982;91(4):1181
mannosidestreptomycin hydrolase  EC 3.2.1.-   *Mannosidases. Methods Enzymol 43:637;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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