encyclopedia of medical concepts
ψ 

Oxo-Acid-Lyases

More information in Books or onNLM PubMed
Definition: Enzymes that catalyze the cleavage of a carbon-carbon bond of a 3-hydroxy acid. (Dorland, 28th ed) EC 4.1.3.     
Examples Anthranilate Synthase; Isocitrate Lyase 		Other names Ketoacid-Lyases; Oxo Acid Lyases; Ketoacid Lyases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,4-dihydroxy-2-naphthoyl-CoA synthase, Staphylococcus aureus  EC 4.1.3.36   *Oxo-Acid-Lyases. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 Nov 1;63(Pt 11):908-13
FTO protein, mouse  EC 4.1.3.15   *Oxo-Acid-Lyases. Science 2007 Nov 30;318(5855):1469-72
beta-methylmalyl-coenzyme A lyase  EC 4.1.3.-   *Oxo-Acid-Lyases. J Bacteriol 2002 Nov;184(21):5999-6006
methylthioalkylmalate synthase 1  EC 4.1.3.-   *Oxo-Acid-Lyases. Plant Physiol 2001 Nov;127(3):1077-88
sialate-pyruvate lyase  EC 4.1.3.-   *Oxo-Acid-Lyases. Eur J Biochem 2001 Dec;268(24):6473-86
Pyc protein, Streptomyces clavuligerus  EC 4.1.3.-   *Bacterial Proteins *Oxo-Acid-Lyases. J Bacteriol 1999 Nov;181(22):6922-8
2-keto-3-deoxy-glycero-galacto-nononic acid 9-phosphate synthetase  EC 4.1.3.-   *Oxo-Acid-Lyases. J Biol Chem 1999 Aug 13;274(33):22949-56
2-methylcitrate synthase  EC 4.1.3.31   *Oxo-Acid-Lyases. Microbiology 1998 Apr;144( Pt 4):929-35
citryl-CoA lyase  EC 4.1.3.34   *Oxo-Acid-Lyases. J Bacteriol 1998 Feb;180(3):647-54
glyoxylate synthetase  EC 4.1.3.-   *Oxo-Acid-Lyases. Eur J Biochem 1993 Jun 15;214(3):889-96
chorismate pyruvate lyase  EC 4.1.3.-   *Oxo-Acid-Lyases Escherichia coli Proteins. FEBS Lett 1992 Aug 3;307(3):347-50
aminodeoxychorismate lyase  EC 4.1.3.-   *Oxo-Acid-Lyases. Proc Natl Acad Sci USA 1990;87(23):9391
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase  EC 4.1.3.-   *Oxo-Acid-Lyases Vitamin K 2. J Bacteriol 1989;171(8):4349
2-phosphinomethylmalic acid synthase  EC 4.1.3.-   *Oxo-Acid-Lyases. J Antibiot (Tokyo) 1988;41(8):1057
aerobactin synthetase  EC 4.1.3.-   *Oxo-Acid-Lyases. J Bacteriol 1986;165(2):570
4-hydroxy-2-ketovalerate aldolase  EC 4.1.3.-   *Oxo-Acid-Lyases. J Bacteriol 1983;155(1):424
4-hydroxy-2-ketopimelate aldolase  EC 4.1.3.-   *Oxo-Acid-Lyases. Methods Enzymol 1982;90(E):277
3-keto-6-acetamidohexanoate cleavage enzyme  EC 4.1.3.-   *Oxo-Acid-Lyases. Arch Biochem Biophys 1980;203(1):437
2,3-dimethyl malate lyase  EC 4.1.3.32   *Oxo-Acid-Lyases. Hoppe Seylers Z Physiol Chem 360(12):1693;1979
malate ATP lyase  0   *Coenzyme A Ligases *Oxo-Acid-Lyases. J Bacteriol 140(2):468;1979; J Biol Chem 248(21):7295;1973
malyl-CoA lyase  EC 4.1.3.24   *Oxo-Acid-Lyases.
3-ketodihydrosphingosine synthetase  EC 4.1.3.-   *Oxo-Acid-Lyases. Am J Clin Nutr 32(1):179;1979; Biochem Biophys Res Commun 83(1):36;1978; Biochim Biophys Acta 306(2):341;1973
3-keto-5-aminohexanoate cleavage enzyme  EC 4.1.3.-   *Oxo-Acid-Lyases. J Biol Chem 252(1):20;1977
4-hydroxy-2-oxovalerate aldolase  EC 4.1.3.-   *Oxo-Acid-Lyases. J Bacteriol 124(2):679;1975
4-hydroxy-2-oxoglutarate aldolase  EC 4.1.3.16   *Oxo-Acid-Lyases Ketoglutaric Acids. Anal Biochem 87(1):56;1978; Biochemistry 15(13):2912;1976; Biochim Biophys Acta 481(1):212;1977; Biochim Biophys Acta 568(1):234;1979; J Biol Chem 244(7):1919;1969; Methods Enzymol 42(C):280;1975; Methods Enzymol 42(C):285;1975
2-hydroxy-3-oxoadipate synthase  EC 4.1.3.15   *Oxo-Acid-Lyases. Biochim Biophys Acta 499(3):321;1977; Ugeskr Laeger 137(12):684;1975
4-hydroxy-4-methyl-2-oxoglutarate aldolase  EC 4.1.3.17   *Oxo-Acid-Lyases. J Biol Chem 247(20):6444;1972
3-hydroxy-3-methylglutaryl-coenzyme A lyase  EC 4.1.3.4   *Oxo-Acid-Lyases. Biochem Med 1979;22(3):365; Biochim Biophys Acta 297(1):22;1973; Biochim Biophys Acta 572(3):541;1979; Clin Chim Acta 1979;95(1):11; Clin Chim Acta 73:373;1976; Clin Chim Acta 90(2):187;1978; Enzyme 22(1):35;1977; J Pediatr 94(1):89;1979; J Pediatr 95(6):1004;1979
homocitrate synthase  EC 2.3.3.14 3-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)  *Oxo-Acid-Lyases. Arch Biochem Biophys 153(2):742;1972; Biochim Biophys Acta 422:390;1976; Mol Gen Genet 172(2):185;1979
decylhomocitrate synthase  EC 4.1.3.29   *Oxo-Acid-Lyases. Eur J Biochem 38(1):32;1973
citrate (pro-3S)-lyase  EC 4.1.3.6   *Oxo-Acid-Lyases *Multienzyme Complexes. Eur J Biochem 80(2):469;1977; Eur J Biochem 86:203;1978; Eur J Biochem 87(1):101;1978; FEBS Lett 1979;105(2):267; FEBS Lett 96(1):175;1978
citramalate lyase  EC 4.1.3.22   *Oxo-Acid-Lyases. Eur J Biochem 80(2):469;1977; FEBS Lett 76(2):280;1977
N-acylneuraminate-9-phosphate synthase  EC 2.5.1.57   *Oxo-Acid-Lyases.
N-acetylneuraminate synthase  EC 2.5.1.56   *Oxo-Acid-Lyases.
N-acetylneuraminate lyase  EC 4.1.3.3   *Oxo-Acid-Lyases. Zentralbl Veterinaermed (B)25(6):452;1978

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy