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Interferons

More information in Books or onNLM PubMed
Definition: Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.  "stimulators" or "inducers"   
Pharmacological Action Antineoplastic Agents; Antiviral Agents
See Also Receptors, Interferon
Examples Interferon Type I; Interferon-gamma 		Other names Interferon
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
inteferon phi2, zebrafish  0   *Interferons *Zebrafish Proteins. J Immunol 2009 Sep 15;183(6):3924-31
interferon phi1, zebrafish  0   *Interferons *Zebrafish Proteins. J Immunol 2009 Sep 15;183(6):3924-31
locteron  0   *Interferons *Recombinant Proteins. J Interferon Cytokine Res 2008 feb;28(2):113-22
interferon-epsilon, human  0   *Interferons. J Immunol 2007 Oct 1;179(7):4542-9
polyethylene glycol-interferon beta-1a  0   *Interferons *Polyethylene Glycols. J Pharmacol Exp Ther 2001 Jun;297(3):1059-66
(2-sulfo-9-fluorenylmethoxycarbonyl)7-interferon-alpha2  0   *Fluorenes *Interferons. Proc Natl Acad Sci U S A 2001 Jan 30;98(3):1212-7
limitin  0   *Cytokines Interferons. Nat Med 2000 Jun;6(6):659-66
IFI27 protein, human  0   *Membrane Proteins Interferons. Cytokine 2000 Mar;12(3):233-8
IFIT3 protein, human  0   *Intracellular Signaling Peptides and Proteins Interferons. Genomics 1998 Dec 1;54(2):267-77
IFIT5 protein, human  0   *Neoplasm Proteins Interferons. Blood Cells Mol Dis 1997 Dec;23(3):337-49
WARS protein, human  EC 6.1.1.2   *Tryptophan-tRNA Ligase Interferons Peptide Termination Factors. EMBO J 1992 Feb;11(2):489-96
interferon regulatory factor-8  0   *Interferon Regulatory Factors Interferons Consensus Sequence. Proc Natl Acad Sci USA 1990;87(10):3743
interferon-induced 56K protein, human  0   *Proteins Interferons. J Interferon Res 1986;6(4):417
interferon eicosapeptide (human lymphoblastoid)  79113-16-9 L-Glutamine, L-seryl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-histidyl-L-seryl-L-leucylglycyl-L-asparaginyl-L-arginyl-L-arginyl-L-alanyl-L-leucyl-L-isoleucyl-L-leucyl-L-leucyl-L-alanyl  *Interferons *Peptide Fragments. Chem Pharm Bull 1981;29(5):1390
interferon repressor protein, mouse  0   *Repressor Proteins Interferons. Antibiotiki 25(2):145;1980

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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