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Insulin-Like Growth Factor II

More information in Books or onNLM PubMed
Definition: A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.     
See Also Receptor, IGF Type 1; Receptor, IGF Type 2 		Other names Somatomedin MSA; Multiplication-Stimulating Activity; IGF-II; Multiplication Stimulating Factor; Multiplication Stimulating Activity; Insulin Like Somatomedin Peptide II; Factor, Multiplication-Stimulating; Somatomedin A; Multiplication-Stimulating Factor; Insulin-Like Somatomedin Peptide II; Insulin Like Growth Factor II; IGF-2
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
insulin-like growth factor II, des(37-40)  0   Insulin-Like Growth Factor II/*analogs & derivatives. Growth Horm IGF Res 2010 Oct;20(5):360-6
IGF2 protein, mouse  0   *Insulin-Like Growth Factor II. Hum Mol Genet 2006 Apr 15;15(8):1259-69
preptin  0   *Insulin-Like Growth Factor II *Peptide Fragments Protein Precursors. Biochem J 2001 Dec 1;360(Pt 2):431-9
insulin-like growth factor II, Leu(27)  132729-29-4   Insulin-Like Growth Factor II/*analogs & derivatives. Endocrinology 1991;128(2):1201
proinsulin-like growth factor II  0   *Insulin-Like Growth Factor II *Protein Precursors. J Lab Clin Med 1990;116(4):555
proinsulin-like growth factor II (117-156)  108688-27-3   *Insulin-Like Growth Factor II *Peptide Fragments *Protein Precursors. Endocrinology 1987;120(5):2050
4-azidobenzoyliodo-insulin-like growth factor II  0   *Azides Insulin-Like Growth Factor II/*analogs & derivatives. J Biol Chem 1985;260(16):9435
preproinsulin-like growth factor II  0   *Insulin-Like Growth Factor II *Protein Precursors Growth Substances. Nature 1984;310(5980):775
IGF2 protein, human  0   *Insulin-Like Growth Factor II. Biochemistry 1982;21(14):3502
multiplication-stimulating activity carrier protein, rat  0   *Carrier Proteins Insulin-Like Growth Factor II. Proc Natl Acad Sci USA 1980;77(12):7252

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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