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Inhibins

More information in Books or onNLM PubMed
Definition: Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively  /biosyn /physiol permitted   
Examples Inhibin-beta Subunits 		Other names Testicular Inhibins; Inhibin, Testicular; Inhibin, Ovarian; Inhibin, Female; Inhibin F; Female Inhibins; Testicular Inhibin; Ovarian Inhibin; Inhibins, Testicular; Inhibins, Female; Inhibin-F; Inhibin; Female Inhibin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
activin beta B, zebrafish  0   *Inhibins *Activins. Genes Dev 1994 Jun 15;8(12):1448-62
inhibin B  0   *Inhibins.
inhibin A  0   *Inhibins.
inhibin alpha 1-26  0   *Inhibins *Peptide Fragments. J Reprod Fertil 1997 Mar;109(2):237-45
inhibin-alpha subunit precursor  0   *Inhibins *Protein Precursors. J Clin Endocrinol Metab 1995 Oct;80(10):2926-32
inhibin-alpha subunit  0   *Inhibins. J Endocrinol 1995 Apr;145(1):35-42
seminal plasma inhibin (85-94), Tyr(85), Cys(Acm)(87)  121637-29-4   *Inhibins *Peptide Fragments. Indian J Exp Biol 1989;27(1):10
alpha-inhibin-92  97812-69-6   *Inhibins. Int J Pept Protein Res 1986;28(5):468
beta-inhibin (67-94)  96182-95-5   *Inhibins *Peptide Fragments. FEBS Lett l985;181(1):57
human inhibin-like peptide (1-31)  92879-83-9   *Inhibins Inhibins. Proc Natl Acad Sci USA 1984;81(17):5399

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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