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Hydroxyeicosatetraenoic Acids

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Definition: Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.     
Examples 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid 		Other names HETE; Acids, Hydroxyeicosatetraenoic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(5,15-dihydroxyeicosanoylamino)ethanesulfonic acid  0   *Hydroxyeicosatetraenoic Acids Taurine/*analogs & derivatives. Biosci Biotechnol Biochem 2010;74(5):1089-91
20-hydroxyeicosa-6(Z),15(Z)-dienoic acid  0   *Hydroxyeicosatetraenoic Acids. Eur J Pharmacol. 2004 Feb 23;486(3):297-306
4-amino-N-(20-hydroxy-eicosa-5(Z),14(Z)-dienoyl) benzenesulfonamide  0   *Hydroxyeicosatetraenoic Acids. Eur J Pharmacol. 2004 Feb 23;486(3):297-306
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid  0   *Hydroxyeicosatetraenoic Acids. Eur J Pharmacol. 2004 Feb 23;486(3):297-306
16-hydroxy-5,8,11,14-eicosatetraenoic acid  0   *Hydroxyeicosatetraenoic Acids. Biochem Pharmacol 2000 Aug 1;60(3):447-55
5-oxo-12-hydroxy-6,8,11,13-eicosatetraenoic acid  0   *Hydroxyeicosatetraenoic Acids. Blood 1999 Feb 1;93(3):1086-96
trioxilin B3  0   *Hydroxyeicosatetraenoic Acids. J Invest Dermatol 1998 Apr;110(4):303-10
13-hydroxy-5,8,11-eicosatrienoic acid  0   *Hydroxyeicosatetraenoic Acids. J Chromatogr B Biomed Appl 1997 Mar 7;690(1-2):332-7
11-hydroxy-5,8,12-eicosatrienoic acid  0   *Hydroxyeicosatetraenoic Acids. J Chromatogr B Biomed Appl 1997 Mar 7;690(1-2):332-7
5,6-dihydroxyeicosatrienoate-1,5-lactone  0   *Hydroxyeicosatetraenoic Acids. J Chromatogr B Biomed Appl 1994 Apr 12;678(2):339-43
13-hydroxyeicosatetraenoic acid  151910-72-4   *Hydroxyeicosatetraenoic Acids. Arch Biochem Biophys 1995 Aug 20;321(2):485-92
10-hydroxyeicosatetraenoic acid  167697-52-1   *Hydroxyeicosatetraenoic Acids. Arch Biochem Biophys 1995 Aug 20;321(2):485-92
7-hydroxyeicosatetraenoic acid  0   *Hydroxyeicosatetraenoic Acids. Arch Biochem Biophys 1995 Aug 20;321(2):485-92
15-hydroxyeicosatrienoic acid  82451-61-4   *Hydroxyeicosatetraenoic Acids. Exp Dermatol 1995 Apr;4(2):74-8
5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid  142828-12-4   *Hydroxyeicosatetraenoic Acids Chemotactic Factors, Eosinophil. J Biol Chem 1992 Jun 25;267(18):12482-8
3-hydroxy-5,8,11,14-eicosatetraenoic acid  135295-02-2   *Hydroxyeicosatetraenoic Acids. FEBS Lett 1991;283(2):195
18-naphthoyl-5,8,11,14-eicosatetraenoic acid methyl ester  133983-27-4   *Hydroxyeicosatetraenoic Acids. J Chromatogr 1990;526(2):525
19-naphthoyl-5,8,11,14-eicosatetraenoic acid methyl ester  133983-28-5   *Hydroxyeicosatetraenoic Acids. J Chromatogr 1990;526(2):525
14(15)-epoxytetraene  114144-28-4   *Hydroxyeicosatetraenoic Acids. Biochem Pharmacol 1990;39(2):355
18-hydroxy-5,8,11,14-eicosatetraenoic acid  21914-83-0   *Hydroxyeicosatetraenoic Acids. J Biol Chem 1989;264(30):17845
5,6-methano-15-hydroxy-7,9,11,13-eicosatetraenoic acid  111037-11-7   *Hydroxyeicosatetraenoic Acids. Adv Exp Med Biol 1988;229:61
15-hydroxy-5,8,11,13 eicosatetraenoic acid methyl ester  70946-44-0   *Hydroxyeicosatetraenoic Acids. Adv Exp Med Biol 1988;229:39
20-hydroxy-5,8,11,14-eicosatetraenoic acid  79551-86-3   *Hydroxyeicosatetraenoic Acids. Biochem Biophys Res Commun 1988;152(3):1269
19-hydroxy-5,8,11,14-eicosatetraenoic acid  79551-85-2   *Hydroxyeicosatetraenoic Acids. Biochem Biophys Res Commun 1988;152(3):1269
11,12-dihydroxyeicosatetraenoic acid  122087-32-5   *Hydroxyeicosatetraenoic Acids. Adv Prostaglandin Thromboxane Leukotriene Res 1987;17A:99
5-fluoro-12-hydroxyeicosatetraenoic acid  109522-29-4   *Hydroxyeicosatetraenoic Acids. Chem Pharm Bull (Tokyo) 1987;35(4):1666
5,20-dihydroxy-6,8,11,14-eicosatetraenoic acid  107373-23-9   *Hydroxyeicosatetraenoic Acids. J Immunol 1986;137(10):3277
15-hydroxy-5,6-oxido-7,9,11,13-eicosatetraenoic acid  94235-42-4   *Hydroxyeicosatetraenoic Acids. FEBS Lett 1986;207(1):127
trioxilin B4  103301-71-9   *Hydroxyeicosatetraenoic Acids. Prostaglandins Leukotrienes Med 1986;22(1):1
trioxilin A4  103301-70-8   *Hydroxyeicosatetraenoic Acids. Prostaglandins Leukotrienes Med 1986;22(1):1
hepoxilin B4  103188-12-1   *Hydroxyeicosatetraenoic Acids. Prostaglandins Leukotrienes Med 1986;22(1):1
hepoxilin A4  103188-13-2   *Hydroxyeicosatetraenoic Acids. Prostaglandins Leukotrienes Med 1986;22(1):1
5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid  71651-85-9   *Hydroxyeicosatetraenoic Acids. J Biol Chem 1986;261(14):6332
5-hydroxyeicosatetraenoic acid lactone  81517-87-5   *Hydroxyeicosatetraenoic Acids. Inflammation 1985;9(4):395
8-hydroxyeicosatetraenoic acid  73179-96-1   *Hydroxyeicosatetraenoic Acids. J Biol Chem 1986;261(2):747
10,11,12-trihydroxy-5,8,14,17-eicosatetraenoic acid  98004-40-1   *Hydroxyeicosatetraenoic Acids. Prostaglandins 1985;29(6):1021
5,15-dihydroxy-6,8,11,13-eicosatetraenoic acid  82200-87-1 6,8,11,13-Eicosatetraenoic acid, 5,15-dihydroxy-, (S-(R*,R*-(E,E,Z,Z)))  *Hydroxyeicosatetraenoic Acids. J Biol Chem 1982;257(12):7056
20-carboxyleukotriene B4  80434-82-8 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))  *Hydroxyeicosatetraenoic Acids. FEBS Lett 1981;130(1):107
14-iodo-15-hydroxyeicosatrienoic acid, omega lactone  78000-89-2 Oxacyclohexadeca-6,9,12-trien-2-one, 15-iodo-16-pentyl  *Hydroxyeicosatetraenoic Acids. Lipids 1981;16(4):246
15-iodo-14-hydroxyeicosatrienoic acid, omega lactone  78000-90-5 Oxacyclopentadeca-6,9,12-trien-2-one, 15-(1-iodohexyl)  *Hydroxyeicosatetraenoic Acids. Lipids 1981;16(4):246
11-hydroxy-5,8,12,14-eicosatetraenoic acid  73151-66-3   *Hydroxyeicosatetraenoic Acids. Nature 1980;288(5787):183
15-hydroxy-5,8,11,13-eicosatetraenoic acid  73945-47-8   *Hydroxyeicosatetraenoic Acids. J Biol Chem 1980;255(13):5996
5-hydroxy-6,8,11,14-eicosatetraenoic acid  72255-35-7 6,8,11,14-eicosatetraenoic acid, 5-hydroxy  *Hydroxyeicosatetraenoic Acids Chemotactic Factors. J Clin Invest 64(5):1457;1979

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