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Hydroxycholecalciferols

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Definition: Hydroxy analogs of vitamin D 3; (CHOLECALCIFEROL); including CALCIFEDIOL; CALCITRIOL; and 24,25-DIHYDROXYVITAMIN D 3.  deficiency: coordinate HYDROXYCHOLECALCIFEROLS /defic (IM) with VITAMIN D DEFICIENCY (IM)   
Pharmacological Action Bone Density Conservation Agents; Vitamins
Examples Calcifediol; Dihydroxycholecalciferols 		Other names D, Hydroxyvitamins; Hydroxycholecalciferol; Hydroxyvitamins D
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-cyclopropyl-2-methylene-19,25,26,27-tetranor-25-aza-1-hydroxyvitamin D  0   *Hydroxycholecalciferols. Steroids. 2012 Feb;77(3):212-23.
16-ene-2-methyl-1,15,25-trihydroxyvitamin D3  0   *Hydroxycholecalciferols. Anticancer Res. 2012 Jan;32(1):311-7.
1alpha,20-dihydroxyvitamin D3  0   *Hydroxycholecalciferols. J Steroid Biochem Mol Biol. 2008 Dec;112(4-5):213-9
1,23,25-trihydroxy-24-oxo-19-norvitamin D(3)  0   *Hydroxycholecalciferols. Steroids 2000 May;65(5):252-65
1-hydroxyvitamin D5  0   *Hydroxycholecalciferols. J Natl Cancer Inst 1997 Feb 5;89(3):212-8
22-(3-(dimethylhydroxymethyl)phenyl)-23,24,25,26,27-pentanor-1-hydroxyvitamin D3  133910-11-9   *Hydroxycholecalciferols. Cancer Res 1993 Sep 1;53(17):3935-42
delta-22-1,25S,26-trihydroxyvitamin D3  144300-56-1   *Hydroxycholecalciferols. J Bone Miner Res 1991 Aug;6(8):893-9
1,24,26-trihydroxy-delta 22-vitamin D3  101558-90-1   *Hydroxycholecalciferols. Biochem Biophys Res Commun 1991;179(1):57
1-hydroxyvitamin D3 diacetate  41461-12-5   *Hydroxycholecalciferols. J Nutr Sci Vitaminol (Tokyo) 1990;36(4):299
1-hydroxyprevitamin D3 diacetate  54712-17-3   *Hydroxycholecalciferols. J Nutr Sci Vitaminol (Tokyo) 1990;36(4):299
MC 969  120336-94-9 9,10-Secochola-5,7,10(19)-triene-1,3-diol, 24-cyclopropyl-, (1alpha,3beta,5Z,7E)  *Hydroxycholecalciferols. Biochem Pharmacol 1990;40(2):333
22-hydroxycholecalciferol  110927-46-3   *Hydroxycholecalciferols. J Steroid Biochem 1987;28(2):147
1,23,25,26-tetrahydroxyvitamin D3  100634-18-2   *Hydroxycholecalciferols. Arch Biochem Biophys 1987;254(1):188
1-hydroxy-22-oxavitamin D3  111687-67-3   *Hydroxycholecalciferols. Chem Pharm Bull (Tokyo) 1986;34(10):4410
1-hydroxy-24,24-dimethyl-22-dehydrovitamin D3  104211-64-5   *Hydroxycholecalciferols. Chem Pharm Bull (Tokyo) 1985;33(11):4815
24,25,26,27-tetranor-23-hydroxyvitamin D3  88200-28-6   *Hydroxycholecalciferols. Biochemistry 1984;23(6):3749
1-hydroxyvitamin D3 3-D-glucopyranoside  91037-29-5 beta-D-Glucopyranosiduronic acid, (1alpha,3beta,5Z,7E)-1-hydroxy-9,10-secocholesta-5,7,10(19)-trien-3-yl, endo-(+-)  *Hydroxycholecalciferols. Int J Vitam Nutr Res 1984;54(1):25
1-hydroxyvitamin D3-cellobioside  89457-70-5 beta-D-Glucopyranoside, (1alpha,3beta,5Z,7E)-1-hydroxy-9,10-secocholesta-5,7,10(19)-trien-3-yl 4-O-beta-D-glucopyranosyl-, (+-)  *Hydroxycholecalciferols. Int J Vitam Nutr Res 1984;54(1):25
11-hydroxyvitamin D3  89321-96-0   *Hydroxycholecalciferols. Biochemistry 1984;23(9):1983
1,23,25-trihydroxy-24-oxo-vitamin D3  87147-48-6 9,10-Secocholesta-5,7,10(19)-trien-24-one, 1,3,23,25-tetrahydroxy-, (1alpha,3beta,5Z,7E)  *Hydroxycholecalciferols. Arch Biochem Biophys 1983;224(2):671
25-hydroxyvitamin D3-26,23-peroxylactone  84070-69-9 1,2-Dioxan-3-one, 4-hydroxy-6-(2-(4-(2-(5-hydroxy-2-methylenecyclohexylidene)ethylidene)octahydro-7a-methyl-1H-inden-1-yl)propyl)-4-methyl  *Hydroxycholecalciferols. J Biol Chem 1982;257(24):14708
23-keto-25-hydroxyvitamin D3  83353-84-8 9,10-Secocholesta-5,7,10(19)-trien-23-one, 3,25-dihydroxy-, (3beta,5Z,7E)  *Hydroxycholecalciferols. Biochem Biophys Res Commun 1982;107(4):1319
1,25,26-trihydroxy-23-oxo-vitamin D3  82095-24-7 9,10-Secocholesta-5,7,10(19)-trien-23-one, 1,3,25,26-tetrahydroxy-, (1alpha,3beta,5Z,7E)  *Hydroxycholecalciferols. J Biol Chem 1982;257(9):5097
23,25,26-trihydroxyvitamin D3  81515-15-3 9,10-Secocholesta-5,7,10(19)-triene-3,23,25,26-tetrol, (3beta,5Z,7E)  *Hydroxycholecalciferols. FEBS Lett 1982;138(1):83
24,25,26-trihydroxyvitamin D3  76355-23-2 9,10-Secocholesta-5,7,10(19)-triene-3,24,25,26-tetrol, (3beta,5Z,7E)  *Hydroxycholecalciferols. Biochemistry 1981;20(26):7385
23,24,25-trihydroxyvitamin D3  80463-20-3 9,10-Secocholesta-5,7,10(19)-triene-3,23,24,25-tetrol, (3beta,5Z,7E)  *Hydroxycholecalciferols. Biochemistry 1981;20(26):7385
1-hydroxyprevitamin D3  41461-13-6   *Hydroxycholecalciferols. J Nutr Sci Vitaminol 1980;26(6):545
24-hydroxyvitamin D3  56720-87-7   *Hydroxycholecalciferols. Biochemistry 1981;20(8):2350
1,25,26-trihydroxyvitamin D3  77372-59-9 9,10-Secocholesta-5,7,10(19)-triene-1,3,25,26-tetrol, (1alpha,3beta,5Z,7E,25S)  *Hydroxycholecalciferols. Biochem Biophys Res Commun 1981;99(1):302
19-hydroxy-10(S),19-dihydrovitamin D3  62077-06-9   *Hydroxycholecalciferols. Biochemistry 1980;19(23):5335
26-hydroxycholecalciferol  69556-15-6 9,10-sechocholesta-5,7,10(19)-triene-3,26-diol, (3 beta,5Z,7E,25R)  *Hydroxycholecalciferols. J Steroid Biochem 1980;13(7):803
24-hydroxy-25-fluorovitamin D3  0   *Hydroxycholecalciferols. Arch Biochem Biophys 1979;197(1):193; J Biol Chem 254(6):2017;1979
1-hydroxy-25-fluorovitamin D3  64164-40-5 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, 25-fluoro-, (1alpha,3beta,5Z,7E)  *Hydroxycholecalciferols. Arch Biochem Biophys 1979;197(1):193; Biochemistry 17(12):2387;1978
1,24,25-trihydroxyvitamin D3  50648-94-7 (3 beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,24,25- tetrol  *Hydroxycholecalciferols. Arch Biochem Biophys 179(1):229;1977; Inborn Errors Calcium Bone Metab WE250 S678i:1;1974; J Biol Chem 252(4):1421;1977; Methods Enzymol 1980;67:529; Proc Soc Exp Biol Med 159(2):204;1978
1-hydroxycholecalciferol  41294-56-8 9,10-secocholesta-,7,10(19)-triene-1 alpha,3 beta-diol  *Hydroxycholecalciferols.
Pharma Action Bone Density Conservation Agents 		Pediatr Res 9(7):486;1975; Scand J Rheumatol 1979:8(4);257; Steroids 23(1):75;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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