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Homocysteine

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Definition: A thiol-containing amino acid formed by a demethylation of METHIONINE.  do not confuse with HOMOCYSTINE   
Examples S-Adenosylhomocysteine 		Other names 2-amino-4-mercaptobutyric acid; L-Isomer Homocysteine; Homocysteine, L Isomer; 2 amino 4 mercaptobutyric acid; Homocysteine, L-Isomer
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
S-(3-fluoropropyl)homocysteine  0   Homocysteine/*analogs & derivatives Fluorine Radioisotopes. J Med Chem 2011 Mar 24;54(6):1860-70
4,4'-selenobis(2-aminobutanoic acid)  0   *Organoselenium Compounds Homocysteine/*analogs & derivatives. Anal Bioanal Chem 2011 Feb;399(5):1765-72
5-(3-amino-3-carboxypropylthio)-3,3-dimethylpentanoic acid  0   *Pentanoic Acids Homocysteine/*analogs & derivatives Betaine-Homocysteine S-Methyltransferase/antagonists & inhibitors. J Med Chem 2009 Jun 25;52(12):3652-65
5-(3-amino-3-carboxypropylthio)-3-methylpentanoic acid  0   *Pentanoic Acids Homocysteine/*analogs & derivatives Betaine-Homocysteine S-Methyltransferase/antagonists & inhibitors. J Med Chem 2009 Jun 25;52(12):3652-65
homocysteinylcobalamin  0   Homocysteine/*analogs & derivatives Vitamin B 12/*analogs & derivatives. Dalton Trans 2006 Nov 28;(44):5269-77
5'-O-(S-trifluoromethylhomocysteinylsulfamoyl)adenosine  0   Adenosine/*analogs & derivatives Homocysteine/*analogs & derivatives Methionine-tRNA Ligase/antagonists & inhibitors. Med Chem 2005 May;1(3):227-37
N-homocysteinylated albumin  0   *Serum Albumin Homocysteine/*analogs & derivatives. J Biol Chem 2002 Aug 23;277(34):30425-8
thioretinaco  0   Homocysteine/*analogs & derivatives Vitamin B 12/*analogs & derivatives. Res Commun Mol Pathol Pharmacol 2002;111(5-6):179-98
S-ribosyl-L-homocysteine  0   Homocysteine/*analogs & derivatives. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3897-900
S-homoadenosyl-L-homocysteine  0   Homocysteine/*analogs & derivatives. J Org Chem. 2002 Nov 15;67(23)8256-60
N-dansylhomocysteine  0   *Dansyl Compounds Homocysteine/*analogs & derivatives. Proc Natl Acad Sci U S A 2001 Aug 14;98(17):9539-44
albumin-S-S-homocysteine  0   *Serum Albumin Homocysteine/*analogs & derivatives. J Biol Chem 2001 Aug 10;276(32):30111-7
propionine  13073-19-3   *Butyric Acids Homocysteine/*analogs & derivatives. Ann Nucl Med 1997 May;11(2):115-22
alpha-methylhomocysteine thiolactone  156574-58-2   Homocysteine/*analogs & derivatives. Life Sci 1997;60(6):341-50
S-(6-purinyl)homocysteine  136040-01-2   Homocysteine/*analogs & derivatives. Drug Metab Dispos Biol Fate Chem 1993 Sep-Oct;21(5):841-5
S-methyl homocysteine thiolactone  146446-26-6   Homocysteine/*analogs & derivatives. J Biol Chem 1993 Mar 25;268(9):6549-53
S-nitrosohomocysteine  139427-42-2   Homocysteine/*analogs & derivatives. J Cardiovasc Pharmacol 1992;20(Suppl 12):S202-4
homocysteinylpropachlor  142353-11-5   *Acetanilides Homocysteine/*analogs & derivatives. Xenobiotica 1992 Apr;22(4):479-85
N-homocysteine thiolactonyl retinamido cobalamin  0   Homocysteine/*analogs & derivatives Vitamin B 12/*analogs & derivatives. Res Comm Chem Pathol Pharmacol 1989;66(1):117
technetium Tc 99m homocysteine  0   *Homocysteine *Organotechnetium Compounds. Int J Rad Appl Instrum (A) 1989;40(7):565
copper-S-(methylthio)homocysteine complex  0   *Organometallic Compounds Homocysteine/*analogs & derivatives Copper. Mol Pharmacol 1988;34(3):401
S-inosylhomocysteine  22365-14-6 Inosine, 5'-S-(3-amino-3-carboxypropyl)-5'-thio  Homocysteine/*analogs & derivatives Inosine/*analogs & derivatives. J Bacteriol 1988;170(9):4376
5-(2-aminoethyl)homocysteine  6367-70-0   Homocysteine/*analogs & derivatives. Biochem Int 1987;15(1):35
S-sulfohomocysteine  28715-19-7 Butyric acid, 2-amino-4-mercapto-, hydrogen sulfate (ester), DL  Homocysteine/*analogs & derivatives. J Biol Chem 1987;262(35):16771
N-homocysteine thiolactonyl retinamide  105918-76-1   Homocysteine/*analogs & derivatives Tretinoin/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1987;56(3):349
rhodium trichloride oxalyl homocysteine thiolactone complex  0   Homocysteine/*analogs & derivatives Rhodium. Cancer Invest 1987;5(1):25
(5'-((N-triphosphoamino)methyl)adenosyl)homocysteine  101249-72-3   Adenosine Triphosphate/*analogs & derivatives Homocysteine/*analogs & derivatives Methionine Adenosyltransferase/antagonists & inhibitors. J Med Chem 1987;30(5):888
S-(1,2-dichlorovinyl)homocysteine  102916-85-8   Homocysteine/*analogs & derivatives. Arch Biochem Biophys 1986;251(2):432
S-(2-hydroxy-2-carboxyethyl)homocysteine  26097-37-0   Homocysteine/*analogs & derivatives. Biochem Int 1985;11(6):789
N-maleamide homocysteine thiolactome amide  86725-08-8   Homocysteine/*analogs & derivatives. Proc Soc Exp Biol Med 1985;180(1):57
palmitoylhomocysteine  76822-97-4   Homocysteine/*analogs & derivatives Liposomes. J Cell Biol 1985;101(2):582
5-(delta-carboxybutyl)homocysteine  88096-03-1 DL-Homocysteine, S-(3-carboxypropyl)  Homocysteine/*analogs & derivatives. J Biol Chem 1983;258(21):12790
homocysteine sulfonamide  83199-31-9 Butanoic acid, 2-amino-4-(aminosulfonyl)-, (S)  Homocysteine/*analogs & derivatives Glutamate Synthase/antagonists & inhibitors. J Biol Chem 1982;257(15):8711
N-acetylhomocysteine  7378-21-4 L-homocysteine, N-acetyl  Homocysteine/*analogs & derivatives. Acta Otolaryngol (Stockh) 1980;89(3-4):240
S-hydroxyethylhomocysteine  61473-66-3 L-Homocysteine, S-(2-hydroxyethyl)  Homocysteine/*analogs & derivatives. J Biochem (Tokyo) 80(6):1327;1976
homocysteinesulfinic acid  31523-80-5   Homocysteine/*analogs & derivatives. Hoppe Seylers Z Physiol Chem 356(9):1369;1975
S-phenyl-DL-homocysteine  52162-05-7 DL-Homocysteine, S-phenyl  Homocysteine/*analogs & derivatives. Mol Pharmacol 10(2):305;1974
homocysteine thiolactone  10593-85-8 3-aminodihydro-2(3H)-thiophenone  Homocysteine/*analogs & derivatives.
Pharma Action Radiation-Protective Agents 		Cancer Res 36(9):3198;1976; Human Genet 43(2):185;1978; J Gen Microbiol 89:371;1975
homocysteic acid  1001-13-4 DL-homocysteate /OD/ 2-amino-4-sulfobutanoic acid  Homocysteine/*analogs & derivatives. Brain Res 101(3):446-79;1975; Brain Res 64(0):397;1973; Brain Res 93(3):409;1975; Contemp Clin Neurophysiol (Suppl 34):285;1978; J Physiol 273(3):791;1977; Metabolism 28(1):80;1979; Neuroendocrinology 26(6):352;1978; Science 192(4237):372;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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