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Glycerol Kinase

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Definition: An enzyme that catalyzes the formation of glycerol 3-phosphate from ATP and glycerol. Dihydroxyacetone and L-glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway. EC 2.7.1.30.      Other names Glycerokinase; Kinase, Glycerol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Hyperglycerolemia  0   *Carbohydrate Metabolism, Inborn Errors Glycerol Kinase/deficiency.
Mrityu protein, Drosophila  EC 2.7.1.30   *Glycerol Kinase *Drosophila Proteins Potassium Channels, Voltage-Gated. Int J Dev Biol 2007;51(3):259-63
GUT1 protein, S cerevisiae  EC 2.7.1.30   *Glycerol Kinase *Saccharomyces cerevisiae Proteins. Science 2003 May 30;300(5624):1394-9160-2
GLK1 protein, Trypanosoma brucei  EC 2.7.1.30   *Glycerol Kinase *Protozoan Proteins. Biol Chem 2000 Nov;381(11):1071-7
2,3-dihydroxypropyl dichloroacetate  93623-15-5   *Acetic Acids *Propylene Glycols Glycerol Kinase/antagonists & inhibitors. Cancer Biochem Biophys 1984;7(3):253

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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