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Germine Acetates

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Definition: Germine derivatives acetylated on any one or more of the hydroxy groups. These compounds are present in many polyester alkaloids which occur in Veratrum and Zygadenus species. They are used as antihypertensive agents, and in some cases, exhibit curare-like activity.      Other names Germine-3-monoacetate; Germine 3 monoacetate; Acetates, Germine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
germine-3,16-diacetate  24381-53-1   *Germine Acetates. Arzneim Forsch 1980;30(6):928
germitrine  560-48-5 germine 3-(1)-2-methylbutyrate 7-acetate 15(d)- 2-hydroxyl-2-methylbutyrate  *Germine Acetates Hydroxyl Radical. Circulation Res 40(1):90;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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