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Fibrous Dysplasia of Bone

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Definition: A disease of bone marked by thinning of the cortex and replacement of bone marrow by gritty fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC). (From Dorland, 28th ed)  GEN or unspecified; prefer specifics; periapical fibrous dysplasia   
Examples Cherubism; Fibrous Dysplasia, Monostotic; Fibrous Dysplasia, Polyostotic
Other names Osteitis Fibrosa Disseminata; Bone Fibrous Dysplasias; Bone Fibrous Dysplasia
 
SubstanceCAS Registry & nameCategoriesSource
Camptodactyly, fibrous tissue hyperplasia, and skeletal dysplasia  0   *Bone Diseases, Developmental *Fibrous Dysplasia of Bone *Hand Deformities, Congenital *Muscular Diseases.
Panostotic fibrous dysplasia  0   *Bone Diseases, Metabolic *Fibrous Dysplasia of Bone *Primary Myelofibrosis.
Florid cemento-osseous dysplasia  0   *Fibrous Dysplasia of Bone *Osteomyelitis.
Lichtenstein syndrome  0   *Fibrous Dysplasia of Bone *Neutropenia *Immunologic Deficiency Syndromes *Facies. Birth Defects Orig. Art. Ser. 8(3): 178-190

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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