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Ethylnitrosourea

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Definition: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.  D25-D26 qualif   
Pharmacological Action Alkylating Agents 		Other names Nitrosoethylurea; N Ethyl N nitrosourea; N-Ethyl-N-nitrosourea
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(2-chloroethyl)-1-nitroso-3-methyl-3-((4-(3-chlorophenyl)amino)quinazolin-6-yl)urea  0   Ethylnitrosourea/*analogs & derivatives Receptor, Epidermal Growth Factor/antagonists & inhibitors. J Med Chem 2006 Jun 15;49(12):3544-52
chloroethylnitrosocarbamoyl-glycinemethylamide  93037-39-9   Ethylnitrosourea/*analogs & derivatives Glycine/*analogs & derivatives. Anticancer Res 1993 Jan-Feb;13(1):81-6
chloroethylnitrosocarbamoyl-alanyl-alanine  93299-11-7   *Dipeptides Ethylnitrosourea/*analogs & derivatives. Anticancer Res 1993 Jan-Feb;13(1):81-6
1,3-diethyl-1-nitrosourea  49540-32-1   Ethylnitrosourea/*analogs & derivatives. J Toxicol Environ Health 1989;28(1):27
1-nitroso-1-ethyl-3-methylurea  72479-23-3   Ethylnitrosourea/*analogs & derivatives. J Toxicol Environ Health 1989;28(1):27
1-(2-methyoxyethyl)-1-nitrosourea  108278-70-2   Ethylnitrosourea/*analogs & derivatives. Jpn J Cancer Res 1988;79(2):181
1-(2-chloroethyl)-3-(1-oxyl-2,2,6,6-tetramethylpiperidinyl)-1-nitrosourea  83144-41-6   *Cyclic N-Oxides Ethylnitrosourea/*analogs & derivatives. Life Sci 1985;36(15):1479
ethylmethanesulfonato-CNU  61866-12-4 Urea, N-(2-chloroethyl)-N'-(2-((methylsulfonyl)oxy)ethyl)-N-nitroso  Ethylnitrosourea/*analogs & derivatives. Oncology 1980;37(3):177
1-(2-hydroxyethyl)-1-nitrosourea  13743-07-2   Ethylnitrosourea/*analogs & derivatives. JNCI 63(6):1469;1979
1-(2-chloroethyl)-1-nitrosourea  2365-30-2   Ethylnitrosourea/*analogs & derivatives. Cancer Res 38(10):3379;1978; Cancer Res 38(8):2363;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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