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Ergot Alkaloids

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Definition: Alkaloids originally isolated from the ergot fungus Claviceps purpurea (Hypocreaceae). They include compounds that are structurally related to ergoline (ERGOLINES) and ergotamine (ERGOTAMINES). Many of the ergot alkaloids act as alpha-adrenergic antagonists.     
Examples Ergolines; Ergotamines
Other names Alkaloids, Ergot; Alkaloids, Clavine; Clavine Alkaloids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aurantioclavine  0   *Ergot Alkaloids. Org Lett 2010 May 7;12(9):2004-7
fumigaclavine B  0   *Ergot Alkaloids *Indole Alkaloids. Chembiochem. 2009 Sep 21;10(14):2325-8
fumigaclavine C  0   *Ergot Alkaloids *Indole Alkaloids. J Pharm Pharmacol 2004 Jun;56(6):775-82
ergotoxine  8006-25-5   *Ergolines Ergot Alkaloids. Nervenarzt 1986;57(3):174
belloid  52499-87-3   *Ergot Alkaloids. Pediatriia 1987(9):99
DCN 203-922  88660-47-3   *Ergot Alkaloids. Experientia 1987;43(10):1125
DHM 32-550  0   *Ergot Alkaloids. Eur J Clin Pharmacol 1984;27(2):131
ergostine  2854-38-8   *Ergot Alkaloids. Experientia 1981;37(3):217
demethylchanoclavine  51704-40-6 2-Propen-1-ol, 3-(4-amino-1,3,4,5-tetrahydrobenz(cd)indol-5-yl)-2-methyl-, (4R-(4alpha,5alpha(E)))  *Ergot Alkaloids. J Nat Products 36(4):390;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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