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Dopa Decarboxylase

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Definition: One of the AROMATIC-L-AMINO-ACID DECARBOXYLASES, this enzyme is responsible for the conversion of dopa to dopamine. It is of clinical importance in the treatment of Parkinson's disease. EC 4.1.1.28.      Other names Decarboxylase, Dopa
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TyDC5 protein, Papaver somniferum  EC 4.1.1.-   *Dopa Decarboxylase *Plant Proteins *Tyrosine Decarboxylase. Plant Physiol 1996 Jan;110(1):43-9
2,3-methano-3-tyrosine  139561-05-0   Tyrosine/*analogs & derivatives Dopa Decarboxylase/antagonists & inhibitors. J Med Chem 1992 Apr 17;35(8):1410-17
NSD 1034  555-62-4 3-((1-methylhydrazino)methyl)phenol  *Hydrazines Dopa Decarboxylase/antagonists & inhibitors. Biochem Pharmacol 28(7):1029;1979
5-(3,4-dihydroxycinnamoyl)salicylic acid  0   *Salicylic Acids Dopa Decarboxylase/antagonists & inhibitors. J Neurochem 28:361;1977
2,3,4-trihydroxybenzylhydrazine  3614-72-0 1,2,3-Benzenetriol, 4-(hydrazinomethyl)  *Hydrazines Dopa Decarboxylase/antagonists & inhibitors. Rev Prat (Paris) 24(15):1212;1974
3-hydroxybenzylhydrazine  637-33-2 3-(hydrazinomethyl)phenol  *Hydrazines Dopa Decarboxylase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Allergy 34(2):103;1979; Brain Res 131(2):313;1977; Catecholamines & Stress W3 19916p:18;1975c; Endocrinology 1980;106(2):463; J Neural Transm 1979;46(3):184; J Neural Transm 1979;46(4):263; J Neural Transm 1980;47(1):1; J Neurochem 1980;34(4):933; Naunyn Schmiedebergs Arch Pharmacol 286:389;1975; Naunyn Schmiedebergs Arch Pharmacol 290(4):347;1975; Naunyn Schmiedebergs Arch Pharmacol 292(2):167;1976; Psychopharmacology 51(3):293;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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