encyclopedia of medical concepts
ψ 
ψ 

Succimer

More information in Books or onNLM PubMed
Definition: A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.  D25-26 qualif   
Pharmacological Action Antidotes; Chelating Agents
Examples Technetium Tc 99m Dimercaptosuccinic Acid 		Other names Dimercaptosuccinic Acid; DMSA; meso Dimercaptosuccinic Acid; Tin Salt Succimer; Ro17977; Ro 1 7977; Rhenium Salt Succimer; Monosodium Salt Succimer; Disodium Salt Succimer; Dipotassium Salt Succimer; Dimercaptosuccinate, Tin; 2,3 Dimercaptosuccinic Acid; meso-Dimercaptosuccinic Acid; Tin Dimercaptosuccinate; Succimer, Tin Salt; Succimer, Rhenium Salt; Succimer, Monosodium Salt; Succimer, Disodium Salt; Succimer, Dipotassium Salt; Succimer, (R*,R*)-(+,-)-IsomerDrugs* : CHEMET
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,3-dimercaptosuccinic acid monocyclohexyl ester  0   Succimer/*analogs & derivatives. Toxicology 2005 Oct 15;214(1-2):39-56
monohexyl 2,3-dimercaptosuccinate  142609-63-0   Succimer/*analogs & derivatives. J Appl Toxiol 1995 May-Jun;15(3):201-6
monoisoamyl-2,3-dimercaptosuccinate  0   Succimer/*analogs & derivatives. Environ Health Perspect 1994 Sep;102 Suppl 3:309-11
monobenzyl 2,3-dimercaptosuccinate  0   Succimer/*analogs & derivatives. Chem Res Toxicol 1994 May-Jun;7(3):367-73
2,3-dimercaptosuccinic acid-cysteine (1-2) mixed disulfide  70206-12-1   Cysteine/*analogs & derivatives Succimer/*analogs & derivatives. J Pharmacol Exp Ther 1993 Dec;267(3):1221-6
dimercaptosuccinic acid monomethyl ester  73618-85-6   Succimer/*analogs & derivatives. Chem Res Toxicol 1991;4(1):107
diisopropyl 2,3-dimercaptosuccinate  118311-05-0   Succimer/*analogs & derivatives. Cell Biol Toxicol 1991;7(2):167
rhenium(V)dimercaptosuccinic acid  133466-85-0   *Succimer *Organometallic Compounds Radioisotopes Rhenium. Int J Rad Appl Instrum (A) 1991;42(2):167
dimethyl mercaptosuccinate  17660-57-0   Succimer/*analogs & derivatives. Toxicol Appl Pharmacol 1989;100(1):96
di-(isoamyl)dimercaptosuccinate  118908-63-7   Succimer/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1988;62(6):327
di-(isobutyl)dimercaptosuccinate  118908-62-6   Succimer/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1988;62(6):327
diethyl dimercaptosuccinate  17660-58-1   Succimer/*analogs & derivatives. Toxicol Lett 1988;41(3):239
stibocaptate  1986-66-9   *Succimer *Organometallic Compounds Antimony. Acta Leiden 45:61;1977; Biochem Pharmacol 1979;28(21):3171; J Helminthol 52(3):227;1978; J Infect Dis 131(5):619;1975; Tropenmed Parasitol 28:447;1977

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy