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Dexetimide

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Definition: A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.  an antiparkinson agent   
Pharmacological Action Antiparkinson Agents; Muscarinic Antagonists; Parasympatholytics 		Other names Dexbenzetimide; Benzetimide; dextro Benzetimide; R16470; R 16470; dextro-Benzetimide; Tremblex; Spasmentral; R-16470; Janssen Brand of Benzetimide Hydrochloride; Dexbenzetimid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-bromodexetimide  162661-31-6   Dexetimide/*analogs & derivatives. Life Sci 1996;58(23):PL337-44
N-methyl-4-iododexetimide  0   Dexetimide/*analogs & derivatives Iodine Radioisotopes. Eur j Nucl Med 1995 Apr;22(4):339-45
4-fluorodexetimide  131948-19-1   Dexetimide/*analogs & derivatives. Life Sci 1991;48(14):1385
2-fluorodexetimide  131948-18-0   Dexetimide/*analogs & derivatives. Life Sci 1991;48(14):1385
4-iododexetimide  137881-49-3   Dexetimide/*analogs & derivatives Iodine Radioisotopes. J Nucl Med 1991;32(1):76
levetimide  21888-99-3   *Dexetimide. J Neurochem 32(2):421;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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