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Clathrin

More information in Books or onNLM PubMed
Definition: The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.  CLATHRIN ASSEMBLY PROTEINS see ADAPTOR PROTEINS, VESICULAR TRANSPORT is available   
Examples Clathrin Heavy Chains; Clathrin Light Chains
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
oncoprotein CLTCL-ALK  0   *Oncogene Proteins, Fusion Clathrin Protein-Tyrosine Kinases. Blood 2000 May 15;95(10):3204-7
Amp1 protein, Dictyostelium discoideum  0   *Protozoan Proteins *Adaptor Proteins, Vesicular Transport Clathrin. Gene 1996 Dec 12;183(1-2):47-51

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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