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Citrate (si)-Synthase

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Definition: Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.      Other names Citrate Synthase; Synthase, Citrate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hsp60 protein, Tetrahymena  0   *Chaperonin 60 *Citrate (si)-Synthase. Genes Cells 2001 FEb;6(2):139-49
methylcitrate synthase  EC 4.1.3.-   *Citrate (si)-Synthase. J Inherit Metab Dis 1994;17(6):738-47
49K protein, Tetrahymena  135343-59-8   *Protozoan Proteins Citrate (si)-Synthase Tetrahymena. Biochem Biophys Res Commun 1991;174(2):1028
palmitoyl thioglycolate  80863-31-6   *Thioglycolates Citrate (si)-Synthase/antagonists & inhibitors. Biochem J 1988;251(3):803

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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