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Butirosin Sulfate

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Definition: A water-soluble aminoglycosidic antibiotic complex isolated from fermentation filtrates of Bacillus circulans. Two components (A and B) have been separated from the complex. Both are active against many gram-positive and some gram-negative bacteria.     
Pharmacological Action Anti-Bacterial Agents 		Other names Butirosins; Sulphate, Butirosin; Sulfate, Butirosin; Sulfate, Anhydrous Butirosin; Anhydrous Butirosin Sulfate; Butirosin Sulphate; Butirosin Sulfate, Anhydrous; Butirosin B; Butirosin A; Butirosin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3'-deoxybutirosin A  55528-48-8   Butirosin Sulfate/*analogs & derivatives. J Antibiot (Tokyo) 1982;35(6):692
5''-amino-3',5''-dideoxybutirosin A  60679-64-3 D-Streptamine, O- 5-amino-5-deoxy-beta-D-xylofuranosyl-(1-5)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)  Butirosin Sulfate/*analogs & derivatives. J Antibiot (Tokyo) 1982;35(6):692
5''-amino-4',5''-dideoxybutirosin A  55480-22-3 D-Streptamine, O-5-amino-5-deoxy-beta-D-xylofuranosyl-(1-5)-O-(2,6-diamino-2,4,6-trideoxy-alpha-D-xylo-hexopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)  Butirosin Sulfate/*analogs & derivatives. J Antibiot (Tokyo) 1982;35(6):692
5''-amino-5''-deoxybutirosin  0   Butirosin Sulfate/*analogs & derivatives. Antimicrob Ag Chemother 10(3):543;1976
aminotrideoxybutirosin A  56182-07-1 D-Streptamine, O-5- amino-5-deoxy-beta-D-xylofuranosyl-(1-5)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-4))-N(1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)  Butirosin Sulfate/*analogs & derivatives. J Antibiotics 28(7):530;1975
Bu-1709El  54333-82-3 (S)-O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-xylofuranosyl-(1-5))-N(1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine  Butirosin Sulfate/*analogs & derivatives. J Antibiot (Tokyo) 26(7):386;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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