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Arachidonate 15-Lipoxygenase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.      Other names 15-Lipoxygenase; Arachidonic Acid 15 Lipoxygenase; Arachidonate 15 Lipoxygenase; 15-Lipoxygenase, Arachidonic Acid; 15-Lipoxygenase, Arachidonate; Arachidonic Acid 15-Lipoxygenase; 15 Lipoxygenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Alox15 protein, mouse  EC 1.13.11.31   *Arachidonate 12-Lipoxygenase *Arachidonate 15-Lipoxygenase. FASEB J 2007 Jul;21(9):2257-66
ALOX15 protein, human  EC 1.13.11.33   *Arachidonate 15-Lipoxygenase. Genomics 1999 Dec 15;62(3):483-9
12-15-lipoxygenase  0   *Arachidonate 12-Lipoxygenase *Arachidonate 15-Lipoxygenase. J Biol Chem 2003 Apr 11;278(15):13350-5
ALOX15B protein, human  EC 1.13.11.33   *Arachidonate 15-Lipoxygenase Cell Cycle Proteins. J Biol Chem 2002 May 3;277(18):16189-201

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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