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Adenylosuccinate Lyase

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Definition: An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. EC 4.3.2.2.      Other names Adenylosuccinase; Lyase, Adenylosuccinate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Adenylosuccinate lyase deficiency  0   *Purine-Pyrimidine Metabolism, Inborn Errors Adenylosuccinate Lyase/deficiency.
adenylosuccinic acid-2',3'-acyclic dialdehyde  0   Adenosine Monophosphate/*analogs & derivatives Adenylosuccinate Lyase/antagonists & inhibitors. Adv Exp Med Biol 1998;431:245-8
adenylosuccinic acid 2',3'-acyclic dialcohol  0   Adenosine Monophosphate/*analogs & derivatives Adenylosuccinate Lyase/antagonists & inhibitors. Adv Exp Med Biol 1998;431:245-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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