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Mitochondrial ADP, ATP Translocases

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Definition: A class of nucleotide translocases found abundantly in mitochondria that function as integral components of the inner mitochondrial membrane. They facilitate the exchange of ADP and ATP between the cytosol and the mitochondria, thereby linking the subcellular compartments of ATP production to those of ATP utilization.     
Examples Adenine Nucleotide Translocator 1; Adenine Nucleotide Translocator 2; Adenine Nucleotide Translocator 3 		Other names Adenine Nucleotide Translocase; ADP,ATP Translocator Protein; ADP,ATP Carrier; Mitochondrial ADP ATP Carriers; ADP-ATP Carriers, Mitochondrial; Mitochondrial ADP-ATP Carriers; Adenine Nucleotide Carrier (Mitochondrial); ATP-ADP Translocase; ATP,ADP-Carrier; ATP Translocase; ADP Translocase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Slc25a41 protein, mouse  0   *Mitochondrial ADP, ATP Translocases. Biochem J 2009 Feb 15;418(1):125-33
Aac3 protein, S cerevisiae  0   *Mitochondrial ADP, ATP Translocases *Saccharomyces cerevisiae Proteins. J Biol Chem 1990 Jul 25;265(21):12711-6
SLC25A31 protein, human  0   *Mitochondrial ADP, ATP Translocases. Dev Biol 2007 Feb 15;302(2):463-76
SAL1 protein, S cerevisiae  0   *Mitochondrial ADP, ATP Translocases *Saccharomyces cerevisiae Proteins. Genetics 2004 Jun;167(2):607-17
stress sensitive B protein, Drosophila  0   *Mitochondrial ADP, ATP Translocases *Drosophila Proteins. Genetics 2003 Nov;165(3);1243-53
2-azido-3'-O-naphthoyl-ADP  0   Adenosine Diphosphate/*analogs & derivatives Mitochondrial ADP, ATP Translocases. Biochemistry. 2000 Sep 19;39(37):11477-87
PET9 protein, S cerevisiae  0   *Mitochondrial ADP, ATP Translocases *Saccharomyces cerevisiae Proteins. J Mol Biol 1998 May 27;277(2):285-308
AATP2 protein, Arabidopsis  0   *Mitochondrial ADP, ATP Translocases *Arabidopsis Proteins. Eur J Biochem 1998 Mar 15;252(3):353-9
AATP1 protein, Arabidopsis  0   *Mitochondrial ADP, ATP Translocases *Arabidopsis Proteins. Plant J 1997 Jan;11(1):73-82
N-(3-iodo-4-azidophenylpropionamido)cysteinyl-5-(2'-thiopyridyl)cysteine-coenzyme A  121368-75-0   *Acyl Coenzyme A *Azides Mitochondrial ADP, ATP Translocases/antagonists & inhibitors. J Biol Chem 1989;264(7):4168
ADP-ATP carrier receptor  0   *Receptors, Cytoplasmic and Nuclear Mitochondrial ADP, ATP Translocases. J Biol Chem 1983;258(7):4071

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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