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Aconitate Hydratase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the reversible hydration of cis-aconitate to yield citrate or isocitrate. It is one of the citric acid cycle enzymes. EC 4.2.1.3.     
Examples Iron Regulatory Protein 1; Iron Regulatory Protein 2 		Other names Isocitrate Hydro-Lyase; Citrate Hydro-Lyase; Aconitase; Isocitrate Hydro Lyase; Hydrolyase, Citrate; Hydro-Lyase, Isocitrate; Hydro-Lyase, Citrate; Hydratase, Aconitate; Citrate Hydro Lyase; Citrate Hydrolyase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aconitase 2, mouse  EC 4.2.1.3.   *Aconitate Hydratase. Proteome Res. 2009 Jul;8(7):3252-64
IRPa protein, Plasmodium falciparum  EC 4.2.1.3   *Aconitate Hydratase *Iron-Regulatory Proteins Membrane Proteins RNA-Binding Proteins Mitochondrial Proteins. Mol Biochem Parasitol 2005 Sep;143(1):29-38
ACO2 protein, human  EC 4.2.1.3   *Aconitate Hydratase. J Med Genet 2003 May;40(5);e73
RpfA protein, bacteria  EC 4.2.1.3   *Aconitate Hydratase *Bacterial Proteins. Mol Plant Microbe Interact 1997 Apr;10(3):407-15
ACN protein, Legionella pneumophila  EC 4.2.1.3   *Aconitate Hydratase *Bacterial Proteins. J Bacteriol 1993 Sep;175(17):5666-76
2,2-difluorocitric acid  139182-83-5   *Citrates Aconitate Hydratase/antagonists & inhibitors ATP Citrate (pro-S)-Lyase/antagonists & inhibitors. Eur J Biochem 1991;202(3):889

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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