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Acetyl-CoA C-Acetyltransferase

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Definition: An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enzymes called thiolase or thiolase-I have referred to this activity or to the activity of ACETYL-COA C-ACYLTRANSFERASE.  do not confuse with ACETYL-COA C-ACYLTRANSFERASE   
See Also Acetyl-CoA C-Acyltransferase 		Other names Acetyl-CoA Acetyltransferase; Acetyl Coenzyme A Acetyltransferase; Acetoacetyl CoA Thiolase; Thiolase, Acetoacetyl CoA; CoA Thiolase, Acetoacetyl; C-Acetyltransferase, Acetyl-CoA; Acetyltransferase, Acetyl-CoA; Acetyl CoA C Acetyltransferase; Acetyl CoA Acetyltransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
HMG CoA lyase deficiency  0   *Amino Acid Metabolism, Inborn Errors Acetyl-CoA C-Acetyltransferase/deficiency.
Hydroxyacyl-coa dehydrogenase, type 2, deficiency  0   *Lipid Metabolism, Inborn Errors Acetyl-CoA C-Acetyltransferase/deficiency.
Cytosolic acetoacetyl-CoA thiolase deficiency  0   *Lipid Metabolism, Inborn Errors Acetyl-CoA C-Acetyltransferase/deficiency.
thl protein, Clostridium pasteurianum  EC 2.3.1.9   *Acetyl-CoA C-Acetyltransferase Bacterial Proteins. Biotechnol Lett. 2006 Aug;28(16):1227-32
Acat1 protein, mouse  EC 2.3.1.9   *Acetyl-CoA C-Acetyltransferase.
ACAT1 protein, human  EC 2.3.1.9   *Acetyl-CoA C-Acetyltransferase.
SK&F 99085  0   *Diphosphonates Acetyl-CoA C-Acetyltransferase/antagonists & inhibitors. Toxicol Sci 1998 Nov;46(1):151-4
3-pentynoyl-S-pantetheine-11-pivalate  119072-37-6   *Alkynes Pantetheine/*analogs & derivatives Acetyl-CoA C-Acetyltransferase/antagonists & inhibitors. J Biol Chem 1991;266(13):8369
Sch 31828  115216-83-6   *Dioxolanes *Heptanoic Acids Acetyl-CoA C-Acetyltransferase/antagonists & inhibitors. J Antibiot (Tokyo) 1988;41(6):794

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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