Definition: A highly effective inhibitor of gastric acid secretion used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-EXCHANGING ATPASE) in the proton pump of GASTRIC PARIETAL CELLS.
Other names Esomeprazole; H 16868; H 168 68; Prilosec; Nexium; H 168-68
omeprazole, sodium bicarbonate drug combination [ Acitrel,Rapinex,SAN 05,Zegerid ] Santarus Inc. has developed an immediate-release formulation of omeprazole in combination with an antacid (sodium bicarbonate) as a powder for suspension, known as Acitrel [SAN 05], and also as Rapine
