Definition: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
a hypoglycemic
Other names Dimethylguanylguanidine; Glucophage; Dimethylbiguanidine
rosiglitazone-metformin combination [ Avandamet,rosiglitazone maleate-metformin hydrochloride combination ] a combination of metformin and rosiglitazone used for treating type 2 diabetes