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ixabepilone

under Epothilones
More information in Books or onNLM PubMed
More on Epothilones Definition: A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).      Other names Epothilone; Epothilon
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ixabepilone [ BMS 247550,BMS-247550,BMS247550 ]
  has antineoplastic activity; epothilone B lactam analogue that induces cell cycle arrest at the G(2)-M phase 		219989-84-1   *Epothilones Tubulin Modulators Clin Cancer Res 2001 May;7(5):1429-37 IXEMPRA KIT

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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