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drotrecogin alfa activated

under Protein C
More information in Books or onNLM PubMed
More on Protein C Definition: A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
drotrecogin alfa activated [ Lilly brand of drotrecogin alfa activated,Xigris,rhAPC ]
  recombiant human activated protein C 		0   *Protein C Recombinant Proteins Fibrinolytic Agents
Pharma Action Anti-Infective Agents 		N Engl J Med 2001 Mar 8;344(10):699-706; N Engl J Med 2006 Oct 19;365(16):1640-1642 XIGRIS

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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