Definition: A form of antibodies consisting only of the variable regions of the heavy and light chains, connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.
Other names Variable Fragments, Single-Chain; Variable Fragment, Single-Chain; Single Chain Variable Fragments; Single Chain Variable Fragment Antibody; Single Chain Variable Fragment Antibodies; Single Chain Variable Fragment; Single Chain Fv Antibody; Single Chain Fv; Single Chain Antibodies; Fv Antibody, Single-Chain; Fragments, Single-Chain Variable; Fragment, Single-Chain Variable; Fv, Single-Chain; Antibody, Single-Chain Fv; Antibodies, Single-Chain; Antibodies, ScFv; Single-Chain Variable Fragments; Single-Chain Variable Fragment Antibody; Single-Chain Variable Fragment Antibodies; Single-Chain Variable Fragment
scFv 763.74 [ scFv763.74 ] a single-chain antibody fragment derived from the monoclonal anti-high molecular weight-melanoma associated antigen antibody 763.74; amino acid sequence in first source
