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ψ
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone
under Amino Acid Chloromethyl Ketones
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Amino Acid Chloromethyl Ketones
Definition
: Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
serine proteinase inhib; DF: AACK
Other names
Peptide Chloromethyl Ketones; Ketones, Peptide Chloromethyl; Chloromethyl Ketones, Peptide
Substance
CAS Registry & name
Categories
Source
Drugs
*
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone [ Ac-DEVD-CMK,Ac-ZVAD-FMK,FK 009,FK-009,FK009,Z-VAD-FMK,Z-VAD.FMK,Z-Val-Ala-Asp-fluoromethylketone,ZVAD-FMK,ZVAD-fluoromethylketone,carbobenzoxyvalyl-alanyl-aspartyl fluoromethyl ketone ]
an interleukin-1beta converting enzyme (ICE)-like protease inhibitor
0
*Amino Acid Chloromethyl Ketones
Caspases/antagonists & inhibitors
Pharma Action
Cysteine Proteinase Inhibitors
;
Neuroprotective Agents
FEBS Lett 1995 Oct 30;374(2):303-8