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epothilone A
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Epothilones
Definition
: A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
Other names
Epothilone; Epothilon
Substance
CAS Registry & name
Categories
Source
Drugs
*
epothilone A [ epothilon A ]
a 16-membered macrolide; mimics the biological effects of taxol; structure given in first source
0
*Epothilones
Pharma Action
Antineoplastic Agents
;
Tubulin Modulators
Cancer Res 1995 Jun 1;55(11):2325-33