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butyrolactone I

under 4-Butyrolactone
More information in Books or onNLM PubMed
More on 4-Butyrolactone Definition: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.      Other names gamma-Butyrolactone; Furanone, tetrahydro-2; 4-Hydroxybutyric Acid Lactone; 1,4-Butanolide; gamma Butyrolactone; Lactone, 4-Hydroxybutyric Acid; Furanone, tetrahydro 2; 4 Hydroxybutyric Acid Lactone; 4 Butyrolactone; Dihydro-2(3H)-furanone; 1,4 Butanolide
SubstanceCAS Registry & nameCategoriesSourceDrugs*
butyrolactone I [ alpha-oxo-beta-(4-hydroxyphenyl)-gamma-(4-hydroxy-m-3,3-dimethylallylbenzyl)-gamma-methoxycarbonyl-gamma-butyrolactone ]
  selective inhibitor of cdk2 & cdc2 kinase; structure given in first source 		87414-49-1   4-Butyrolactone/*analogs & derivatives
Pharma Action Protein Kinase Inhibitors 		Oncogene 1993 Sep;8(9):2425-32

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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