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R 82913

under Benzodiazepines
More information in Books or onNLM PubMed
More on Benzodiazepines Definition: A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.  do not confuse with BENZODIAZEPINONES    Other names Benzodiazepine Compounds; Benzodiazepine
SubstanceCAS Registry & nameCategoriesSourceDrugs*
R 82913 [ 4,5,6,7-tetrahydro-9-chloro-5-methyl-6-(3-methyl-2-butenyl)imidazo(4,5,1-jk)(1,4)benzodiazepin-2-(1H)-thione,9-CMBIB,9-Cl-TIBO,9-chloro-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo(4,5,1-jk)(1,4)benzodiazepine-2-(1H)-thione,R 82913, (R)-isomer,R-82913,R82913 ]
  antiviral target on reverse transcriptase of HIV-1 revealed by above cpd; structure given in first source; RN given is for (S)-isomer 		126347-69-1 Imidazo(4,5,1-jk)(1,4)benzodiazepine-2(1H)-thione, 9-chloro-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)-, (S)  *Benzodiazepines *Imidazoles HIV Reverse Transcriptase/antagonists & inhibitors
Pharma Action Reverse Transcriptase Inhibitors; Anti-HIV Agents 		Proc Natl Acad Sci USA 1991;88(4):1451

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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