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AFDX 384

under Pirenzepine
More information in Books or onNLM PubMed
More on Pirenzepine Definition: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.      Other names Pirenzepin ratiopharm; Piren basan; LS519; LS 519; Dihydrochloride, Pirenzepine; ratiopharm Brand of Pirenzepine Dihydrochloride; pirenzepin von ct; ct-Arzneimittel Brand of Pirenzepine Dihydrochlori; Ulgescum; Sagitta Brand of Pirenzepine Dihydrochloride; Ulcoprotect; Pyrenzepine; Pirenzepine Dihydrochloride; Pirenzepin-ratiopharm; Pirenzepin; Piren-basan; LS-519; L-S 519; Gastrozepin; Gastrotsepin
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AFDX 384 [ 5,11-dihydro-11-(((2-(2-((dipropylamino)methyl)-1-piperidinyl)ethyl)amino)carbonyl)-6H-pyrido(2,3-b)(1,4)-benzodiazepin-6-one methanesulfonate,AF-DX 384 ]
  structure given in first source
118290-27-0 11H-Pyrido(2,3-b)(1,4)benzodiazepine-11-carboxamide, N-(2-(2-((dipropylamino)methyl)-1-piperidinyl)ethyl)-5,6-dihydro-6-oxo-, monomethanesulfonate  Pirenzepine/*analogs & derivatives
Pharma Action Parasympatholytics
Biochem Pharmacol 1990;40(7):1674

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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