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lobucavir

under Guanine
More information in Books or onNLM PubMed
More on Guanine Definition:   do not confuse with GUANIDINES; /biosyn /physiol permitted; guanine riboside, guanine ribonucleoside   
SubstanceCAS Registry & nameCategoriesSourceDrugs*
lobucavir [ 2-amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-6H-purin-6-one,9-(2,3-bis-(hydroxymethyl)-1-cyclobutyl)guanine,BMS 180194,BMS-180194,C-OXT-G,SQ 33054,SQ 34514,SQ-33054,carbocyclic oxetanocin G,SQ-34,514,cyclobut-G ]
  structure given in first source; inhibits the replication of HIV virus in T cells, monocytes & macrophages in vitro by inhibiting DNA polymerase and viral DNA synthesis 		126062-18-8   Guanine/*analogs & derivatives DNA-Directed DNA Polymerase/antagonists & inhibitors Reverse Transcriptase Inhibitors
Pharma Action Enzyme Inhibitors; Anti-HIV Agents 		Antimicrob Agents Chemother 1990;34(2):287

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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