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fosphenytoin

under Phenytoin
More information in Books or onNLM PubMed
More on Phenytoin Definition: An anticonvulsant that is used in a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.      Other names Fenitoin; Diphenylhydantoin; Diphenylhydantoinate, Sodium; Sodium Diphenylhydantoinate; Hydantol; Epanutin; Epamin; Dilantin; Dihydan; Difenin; Antisacer; 5,5-Diphenylhydantoin Drugs: PHENYTOIN SODIUMDIPHENYLAN SODIUM; DILANTIN-30; PHENYTOIN; DILANTIN; EXTENDED PHENYTOIN SODIUM; PHENYTEX; PHENYTEK; PROMPT PHENYTOIN SODIUM; DILANTIN-125;
SubstanceCAS Registry & nameCategoriesSourceDrugs*
fosphenytoin [ 3-(hydroxymethyl)phenytoin disodium phosphate,3-(hydroxymethyl)phenytoin phosphate ester,ACC 9653,ACC-9653,Cerebyx,HMPDP,Prodilantin,fosphenytoin sodium,fosphenytoin, disodium salt ]
  structure given in first & second source
93390-81-9 2,4-Imidazolidinedione, 5,5-diphenyl-3-((phosphonooxy)methyl)-, (SP-4-2)  Phenytoin/*analogs & derivatives Prodrugs
Pharma Action Anticonvulsants
J Pharm Sci 1984;73(8):1080; J Pharm Sci 1984;73(8):1087 CEREBYX; FOSPHENYTOIN SODIUM

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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