Definition: A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Other names Diaminodiphenylsulfone; Sulfonyldianiline; Sulfone, 4,4'-Diaminophenyl; 4,4' Diaminophenyl Sulfone; Sulfona; Orsade Brand of Dapsone; Mex-America Brand of Dapsone; Fatol Brand of Dapsone; Disulone; Diaphenylsulfone; Dapson-Fatol; Dapsoderm-X; DADPS; Avlosulfone; 4,4'-Diaminophenyl Sulfone
