antibiotic G 418 (definition)

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ψ	antibiotic G 418 under Gentamicins

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Definition: A complex of three different closely related aminoglycoside sulfates, Gentamicins C1, C2, and C1(subA), obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (GENETIC TRANSLATION).

Other names Gentamycin; Gentamicin Sulfate (USP); Gentacycol; Garamycin; G-Myticin; Gentavet; Sulfate, Gentamicin; G Myticin; Genticin; Gentamycins; Gentamicin Sulfate; Gentamicin; GMyticin

Drugs: APOGEN U-GENCIN; GENOPTIC; GENTAFAIR; GARAMYCIN; GENTAMICIN; GENTACIDIN; GENTAK; GENTAMICIN SULFATE; PRED-G; BRISTAGEN; GENTAMICIN SULFATE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER; ISOTONIC GENTAMICIN SULFATE IN PLASTIC CONTAINER;

Substance	CAS Registry & name	Categories	Source	Drugs*
antibiotic G 418 [ G 418 sulfate,G-418,G418,Geneticin,antibiotic G-418 ] from Micromonospora rhodorangea	49863-47-0 O-2-amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-D-streptamine	Gentamicins Pharma Action* Amebicides; Coccidiostats	Am J Vet Res 38(9):1293;1977; Antimicrob Agents Chemother 7(6):811;1975; Arzneim Forsch 1979;29(11):1695

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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