encyclopedia of medical concepts
ψ
alphaxalone
under Pregnanediones
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Pregnanediones
Definition
: Pregnane derivatives in which two side-chain methyl groups or two methylene groups in the ring skeleton (or a combination thereof) have been oxidized to keto groups.
Other names
Dioxopregnanes; Diketopregnanes
Substance
CAS Registry & name
Categories
Source
Drugs
*
alphaxalone [ alfaxalone,alfaxolone,alphaxalone, (3alpha)-isomer,alphaxalone, (3alpha,5beta)-isomer,alphaxalone, (3beta,5alpha)-isomer,alphaxalone, (3beta,5beta)-isomer,delta(16)-alfaxalone ]
constituent of alphadione; RN given refers to (3alpha,5alpha)-isomer; structure
23930-19-0 3 alpha-
hydroxy-
5 alpha-
pregnane-
11,20-
dione
*Pregnanediones
Pharma Action
Anesthetics
Arzneimittelforsch 25(10):1603;1975; Biochem Pharmacol 1980;29(2):248; Br J Anaesth 47(8):902;1975; Br J Pharmacol 58:347;1976; Br J Pharmacol 58:359;1976; Br J Pharmacol 59(3):508;1977; Jap J Anesthesiol 23(6):527;1974; Nature 256(5514):179;1975; Vet Rec 102(13):283;1978
