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drotaverin

under Papaverine
More information in Books or onNLM PubMed
More on Papaverine Definition: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.      Other names Hydrochloride, Papaverine; Pavatym; Pavabid; Papaverine Hydrochloride; Cerespan
SubstanceCAS Registry & nameCategoriesSourceDrugs*
drotaverin [ No-shpa,No-spa,Nospan,Nospanum,dihydroisoperparine,drotaverin hydrochloride,drotaverine,isodihydroperparine ]
  Hungarian drug; RN given refers to parent cpd; structure 		14009-24-6 1-benzyl-3',4',6,7-tetraethoxy-1,2,3,4- tetrahydroisoquinoline  Papaverine/*analogs & derivatives
Pharma Action Analgesics; Parasympatholytics; Vasodilator Agents 		Farm Z 5:88;1977; Fiziol Zh 24(3):366;1978; Acta Med Acad Sci Hung 31(3-4):157;1974; Acta Pharm Hung 48(suppl):13;1979; Acta Pharm Hung 49(2):50;1979; Acta Physiol Acad Sci Hung 1979;53(3):369; Basic Res Cardiol 71(3):264;1976; Eur J Drug Metab Pharmacokinet 1979;4(4):213; Farmakol Toksikol 38(3):324;1975; Farmakol Toksikol 39(3):304;1976; Farmakol Toksikol 40(5):547;1977; Fiziol Zh 61(10):1539;1975; Khirurgiia 10:85;1978; Pharm Acta Helv 1979;54(12):363; Pharm Acta Helv 1979;54(7-8):210; Pharmazie 30(3):174;1975; Vestn Oftalmol 2:71;1978; Vestn Oftalmol 5:68;1976; Vrach Delo 2:60;1977; Vrach Delo 3:13;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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