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geldanamycin

under Benzoquinones
More information in Books or onNLM PubMed
More on Benzoquinones Definition: Benzene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.      Other names p-Benzoquinones; o-Benzoquinones; 2,5-Cyclohexadiene-1,4-Diones; Benzodiones; 1,4-Benzoquinones; 1,2-Benzoquinones
SubstanceCAS Registry & nameCategoriesSourceDrugs*
geldanamycin [ geldanomycin ]
  unlike the related ansamycins, geldanamycin possesses a methoxyl at C17 on the quinone; from culture filtrates of Streptomyces hygroscopicus var. geldanus var. Nova. 		30562-34-6   *Benzoquinones *Lactams, Macrocyclic Protein-Tyrosine Kinases/antagonists & inhibitors HSP90 Heat-Shock Proteins
Pharma Action Antibiotics, Antineoplastic; Antiviral Agents; Enzyme Inhibitors; Cysteine Proteinase Inhibitors 		Cancer Treat Rep 61(5):815;1977; J Am Chem Soc 99(10):3541;1977; J Antibiot (Tokyo) 23(9):442;1970; J Antibiot(Tokyo) 1979;32(8):849; Mol Pharmacol 14:422;1978; Proc Soc Exp Biol Med 155:461;1977

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